細胞名稱

人膀胱癌細胞VM-CUB-3

貨物編碼

BFN6021441

產品規格

T25培養瓶x1

1.5ml凍存管x2

細胞數量

1x10^6

1x10^6

保存溫度

37℃

-198℃

運輸方式

常溫保溫運輸

干冰運輸

安全等級

1

用途限制

僅供科研用途        3類

培養體系

DMEM高糖（不含丙酮酸鈉）+10%FBS+1%三抗

培養溫度

37℃

二氧化碳濃度

5%

簡介

人膀胱癌細胞VM-CUB-3取自女性供體，貼壁培養。

注釋

Problematic cell line: Partially contaminated. Some stocks are contaminated by VM-CUB-1 (PubMed=3708594; PubMed=20143388). Although PubMed=26621286 shows it to be different from VM-CUB-1.

Part of: BLA-40 bladder carcinoma cell line panel.

Part of: UBC-40 urothelial bladder cancer cell line index.

Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00102.

Doubling time: 26 hours (PubMed=3708594).

Omics: CNV analysis.

Omics: Deep exome analysis.

Omics: SNP array analysis.

Omics: Transcriptome analysis.

突變信息

TERT c.1-124C>T (c.228C>T) (C228T); Note=In promoter (PubMed=24035680).

Homozygous for TP53 p.Pro278Leu (c.833C>T) (ClinVar=VCV000232497) (PubMed=27270441).

STR信息

Amelogenin X

CSF1PO 12

D5S818 11

D7S820 8,9

D13S317 9,12

D16S539 12

TH01 9.3

TPOX 8

vWA 16

參考文獻

PubMed=25997541; DOI=10.1186/s12864-015-1450-3

 Earl J., Rico D., Carrillo-de-Santa-Pau E., Rodriguez-Santiago B., Mendez-Pertuz M., Auer H., Gomez G., Grossman H.B., Pisano D.G., Schulz W.A., Perez-Jurado L.A., Carrato A., Theodorescu D., Chanock S.J., Valencia A., Real F.X.

 The UBC-40 Urothelial Bladder Cancer cell line index: a genomic resource for functional studies.

 BMC Genomics 16:403-403(2015)

PubMed=26621286; DOI=10.1186/s12864-015-2227-4

 Earl J., Rico D., Carrillo-de-Santa-Pau E., Rodriguez-Santiago B., Mendez-Pertuz M., Auer H., Gomez G., Grossman H.B., Pisano D.G., Schulz W.A., Perez-Jurado L.A., Carrato A., Theodorescu D., Chanock S.J., Valencia A., Real F.X.

 Erratum to: The UBC-40 Urothelial Bladder Cancer cell line index: a genomic resource for functional studies.

 BMC Genomics 16:1019-1019(2015)

PubMed=27270441; DOI=10.1038/onc.2016.172

 Nickerson M.L., Witte N., Im K.M., Turan S., Owens C., Misner K., Tsang S.X., Cai Z., Wu S., Dean M., Costello J.C., Theodorescu D.

 Molecular analysis of urothelial cancer cell lines for modeling tumor biology and drug response.

 Oncogene 36:35-46(2017)

PubMed=29732388; DOI=10.3233/BLC-180167

 Zuiverloon T.C.M., de Jong F.C., Costello J.C., Theodorescu D.

 Systematic review: characteristics and preclinical uses of bladder cancer cell lines.

 Bladder Cancer 4:169-183(2018)